Journal Article
G. Jin, Nakhleh, L., Snir, S., and Tuller, T., Inferring phylogenetic networks by the maximum parsimony criterion: a case study, Molecular Biology and Evolution, vol. 24, pp. 324-337, 2007.
D. Wen, Yu, Y., Zhu, J., and Nakhleh, L., Inferring phylogenetic networks using PhyloNet, Systematic Biology, vol. 67, no. 4, pp. 735-740, 2018.PDF icon phylonet3.pdf (144.21 KB)
K. Liu, Steinberg, E., Yozzo, A., Song, Y., Kohn, M. H., and Nakhleh, L., Interspecific introgressive origin of genomic diversity in the house mouse, Proceedings of the National Academy of Sciences, vol. 112, no. 1, pp. 196-201, 2015.PDF icon LiuEtAl-PNAS2014.pdf (24.54 MB)
M. W. Hahn and Nakhleh, L., Irrational Exuberance for Resolved Species Trees, Evolution, vol. 70, no. 1, pp. 7-17, 2016.PDF icon HahnNakhleh2016.pdf (433.49 KB)
Y. Lu, Muller, M., Smith, D., Dutta, B., Mourov, K., Iadevaia, S., Ruths, D., Tseng, J. - T., Yu, S., Yu, Q., Nakhleh, L., Balazsi, G., Donnelly, J., Schurdak, M., Morgan-Lappe, S., Fesik, S., Ram, P. T., and Mills, G. B., Kinome siRNA-phosphoproteomic screen identifies networks regulating AKT signaling, Oncogene, vol. 30, pp. 4567-4577, 2011.PDF icon Oncogene2011.pdf (905.3 KB)
S. Iadevaia, Nakhleh, L., Azencott, R., and Ram, P. T., Mapping network motif tunability and robustness in the design of synthetic signaling circuits, PLoS One, vol. 9, no. 3, p. e91743, 2014.PDF icon IadevaiaEtAl-PLoSOne14.pdf (1.01 MB)
B. J. Grindel, Martinez, J. R., Tellman, T. V., Harrington, D. A., Zafar, H., Nakhleh, L., Chung, L., and Farach-Carson, M. C., Matrilysin/MMP-7 Cleavage of Perlecan/HSPG2 Complexed with Semaphorin 3A Supports FAK-Mediated Stromal Invasion by Prostate Cancer Cells, Scientific Reports, vol. 8, p. 7262, 2018.PDF icon GrindelEtAl.pdf (2.28 MB)
Y. Yu, Dong, J., Liu, K., and Nakhleh, L., Maximum Likelihood Inference of Reticulate Evolutionary Histories, Proceedings of the National Academy of Sciences, vol. 111, no. 46, pp. 16448-16453, 2014.PDF icon PNAS-2014-YuEtAl.pdf (1.55 MB)
G. Jin, Nakhleh, L., Snir, S., and Tuller, T., Maximum likelihood of phylogenetic networks, Bioinformatics, vol. 22, pp. 2604-2611, 2006.
Y. Yu and Nakhleh, L., A Maximum Pseudo-likelihood Approach for Phylogenetic Networks, BMC Genomics, vol. 16, no. Suppl 10, p. S10, 2015.PDF icon YuNakhleh-BMCGenomics2015.pdf (1.75 MB)
L. Nakhleh, A metric on the space of reduced phylogenetic networks, IEEE/ACM Transactions on Computational Biology and Bioinformatics, vol. 7, pp. 218-222, 2010.PDF icon tcbb-Metric.pdf (287.01 KB)
N. Berestovsky, Zhou, W., Nagrath, D., and Nakhleh, L., Modeling Integrated Cellular Machinery Using Hybrid Petri-Boolean Networks, PLoS Computational Biology, vol. 9, no. 11, p. e1003306, 2013.PDF icon BerestovskyEtAl13.pdf (1.66 MB)
H. Zafar, Wang, Y., Nakhleh, L., Navin, N., and Chen, K., Monovar: single nucleotide variant detection in single cells, Nature Methods, vol. 13, no. 6, pp. 505-507, 2016.PDF icon ZafarEtAl-NMETH2016.pdf (1.51 MB)
G. Saxer, Krepps, M. D., Merkley, E. D., Ansong, C., Kaiser, B. L. Deatherage, Valovska, M. - T., Ristic, N., Yeh, P. T., Prakash, V. P., Leiser, O. P., Nakhleh, L., Gibbons, H. S., Kreuzer, H. W., and Shamoo, Y., Mutations in global regulators lead to metabolic selection during adaptation to complex environments, PLoS Genetics, vol. 10, no. 12, p. e1004872, 2014.PDF icon SaxerEtAl-PLoSGenetics2014.pdf (1.99 MB)
T. Ruths and Nakhleh, L., ncDNA and drift drive binding site accumulation, BMC Evolutionary Biology, vol. 12, p. 159, 2012.PDF icon RuthsNakhleh-BMCEvolBiol2012.pdf (659.08 KB)
E. Bapteste, van Iersel, L., Janke, A., Kelchner, S., Kelk, S., McInerney, J. O., Morrison, D. A., Nakhleh, L., Steel, M., Stougie, L., and Whitfield, J., Networks: Expanding evolutionary thinking, Trends in Genetics, vol. 29, no. 8, pp. 439-441, 2013.PDF icon TIG2013.pdf (179.16 KB)
T. Ruths and Nakhleh, L., Neutral forces acting on intragenomic variability shape the E. coli regulatory network topology, Proceedings of the National Academy of Sciences, vol. 110, no. 19, pp. 7754-7759, 2013.PDF icon RuthsNakhleh-PNAS13.pdf (2.57 MB)
Y. Yu, Barnett, R. M., and Nakhleh, L., Parsimonious Inference of Hybridization in the Presence of Incomplete Lineage Sorting, Systematic Biology, vol. 62, no. 5, pp. 738-751, 2013.PDF icon YuEtAl-SystBiol2013.pdf (1.55 MB)
G. Jin, Nakhleh, L., Snir, S., and Tuller, T., Parsimony Score of Phylogenetic Networks: Hardness Results and a Linear-time Heuristic, IEEE/ACM Transactions on Computational Biology and Bioinformatics, vol. 6, pp. 495-505, 2009.
L. Nakhleh, Ringe, D., and Warnow, T., Perfect Phylogenetic Networks: A New Methodology for Reconstructing the Evolutionary History of Natural Languages, LANGUAGE, Journal of the Linguistic Society of America, vol. 81, pp. 382-420, 2005.
B. M. E. Moret, Nakhleh, L., Warnow, T., Linder, C. R., Tholse, A., Padolina, A., Sun, J., and Timme, R., Phylogenetic networks: modeling, reconstructibility, and accuracy, IEEE/ACM Transactions on Computational Biology and Bioinformatics, vol. 1, pp. 13–23, 2004.
L. Nakhleh and Wang, L. S., Phylogenetic Networks: Properties and Relationship to Trees and Clusters, LNCS Transactions on Computational Systems Biology, II, vol. 3680, pp. 82-99, 2005.
C. Than, Ruths, D., and Nakhleh, L., PhyloNet: A Software Package for Analyzing and Reconstructing Reticulate Evolutionary Relationships, BMC Bioinformatics, vol. 9, p. 322, 2008.
S. Takuno, Kado, T., Sugino, R. P., Nakhleh, L., and Innan, H., Population genomics in bacteria: A case study of Staphylococcus aureus., Molecular Biology and Evolution, vol. 29, no. 2, pp. 797-800, 2012.PDF icon TakunoEtAl-MBE11.pdf (933.28 KB)
Y. Wang, Ogilvie, H. A., and Nakhleh, L., Practical Speedup of Bayesian Inference of Species Phylogenies by Restricting the Space of Gene Trees, Molecular Biology and Evolution, vol. 37, pp. 1809-1818, 2020.PDF icon MBE2020.pdf (502.98 KB)