Journal Article
G. Jin, Nakhleh, L., Snir, S., and Tuller, T.,
“Maximum likelihood of phylogenetic networks”,
Bioinformatics, vol. 22, pp. 2604-2611, 2006.
B. J. Grindel, Martinez, J. R., Tellman, T. V., Harrington, D. A., Zafar, H., Nakhleh, L., Chung, L., and Farach-Carson, M. C.,
“Matrilysin/MMP-7 Cleavage of Perlecan/HSPG2 Complexed with Semaphorin 3A Supports FAK-Mediated Stromal Invasion by Prostate Cancer Cells”,
Scientific Reports, vol. 8, p. 7262, 2018.
GrindelEtAl.pdf (2.28 MB) Y. Lu, Muller, M., Smith, D., Dutta, B., Mourov, K., Iadevaia, S., Ruths, D., Tseng, J. - T., Yu, S., Yu, Q., Nakhleh, L., Balazsi, G., Donnelly, J., Schurdak, M., Morgan-Lappe, S., Fesik, S., Ram, P. T., and Mills, G. B.,
“Kinome siRNA-phosphoproteomic screen identifies networks regulating AKT signaling”,
Oncogene, vol. 30, pp. 4567-4577, 2011.
Oncogene2011.pdf (905.3 KB) K. Liu, Steinberg, E., Yozzo, A., Song, Y., Kohn, M. H., and Nakhleh, L.,
“Interspecific introgressive origin of genomic diversity in the house mouse”,
Proceedings of the National Academy of Sciences, vol. 112, no. 1, pp. 196-201, 2015.
LiuEtAl-PNAS2014.pdf (24.54 MB) D. Wen, Yu, Y., Zhu, J., and Nakhleh, L.,
“Inferring phylogenetic networks using PhyloNet”,
Systematic Biology, vol. 67, no. 4, pp. 735-740, 2018.
phylonet3.pdf (144.21 KB) G. Jin, Nakhleh, L., Snir, S., and Tuller, T.,
“Inferring phylogenetic networks by the maximum parsimony criterion: a case study”,
Molecular Biology and Evolution, vol. 24, pp. 324-337, 2007.
J. Zhu, Yu, Y., and Nakhleh, L.,
“In the light of deep coalescence: Revisiting trees within networks”,
BMC Bioinformatics, vol. 17, no. Suppl 14, p. 415, 2016.
ZhuYuNakhleh-BMCBioinfo2016.pdf (1.06 MB) T. Shigaki, Rees, I., Nakhleh, L., and Hirschi, K.,
“Identification of Three Distinct Phylogenetic Groups of CAX Cation/Proton Antiporters”,
Journal of Molecular Evolution, vol. 63, pp. 815-825, 2006.
X. Fan, Chaisson, M., Nakhleh, L., and Chen, K.,
“HySA: A Hybrid Structural variant Assembly approach using next generation and single-molecule sequencing technologies”,
Genome Research, vol. 27, pp. 793-800, 2017.
Genome Res.-2017-Fan-793-800.pdf (476.55 KB) K. Liu, Dai, J., Truong, K., Song, Y., Kohn, M. H., and Nakhleh, L.,
“An HMM-based comparative genomic framework for detecting introgression in eukaryotes”,
PLoS Computational Biology, vol. 10, no. 6, p. e1003649, 2014.
LiuEtAl-PLoSCB14.pdf (1.3 MB) D. Ruths, Nakhleh, L., Iyengar, M. S., Reddy, S. A. G., and Ram, P. T.,
“Graph-theoretic Hypothesis Generation in Biological Signaling Networks”,
Journal of Computational Biology, vol. 13, pp. 1546-1557, 2006.
Y. Yu, Jermaine, C., and Nakhleh, L.,
“Exploring phylogenetic hypotheses via Gibbs sampling on evolutionary networks”,
BMC Genomics, vol. 17, no. Suppl 10, p. 784, 2016.
YuJermaineNakhleh-BMCGenomics2016.pdf (965.19 KB) F. Barbancon, Evans, S., Nakhleh, L., Ringe, D., and Warnow, T.,
“An experimental study comparing linguistic phylogenetic reconstruction methods”,
Diachronica, vol. 30, no. 2, pp. 143-170, 2013.
Diachronica13.pdf (575.02 KB) G. A. Bravo, Antonelli, A., Bacon, C. D., Bartoszek, K., Blom, M. P. K., Huynh, S., Jones, G., Knowles, L. L., Lamichhaney, S., Marcussen, T., Morlon, H., Nakhleh, L., Oxelman, B., Pfeil, B., Schliep, A., Wahlberg, N., Werneck, F. P., Wiedenhoeft, J., .Willows-Munro, S., and Edwards, S. V.,
“Embracing heterogeneity: coalescing the Tree of Life and the future of phylogenomics”,
PeerJ, vol. 7, p. e6399, 2019.
PeerJ2019.pdf (3.72 MB) G. Jin, Nakhleh, L., Snir, S., and Tuller, T.,
“Efficient parsimony-based methods for phylogenetic network reconstruction”,
Bioinformatics, vol. 23, pp. e123-e128, 2006.
C. Than, Sugino, R., Innan, H., and Nakhleh, L.,
“Efficient Inference of Bacterial Strain Trees From Genome-scale Multi-locus Data”,
Bioinformatics, vol. 24, pp. i123-i131, 2008.
Z. Zhu, Liu, X., Ogilvie, H. A., and Nakhleh, L.,
“A Divide-and-Conquer Method for Scalable Phylogenetic Network Inference from Multi-locus Data”,
Bioinformatics (ISMB 19 Proceedings), vol. 35, pp. i370-i378, 2019.
ZhuEtAl-ISMB19.pdf (668.97 KB) L. Nakhleh, Roshan, U., John, S. K., Sun, J., and Warnow, T.,
“Designing Fast Converging Phylogenetic Methods”,
Bioinformatics, vol. 17, pp. S190–S198, 2001.
C. Than, Ruths, D., Innan, H., and Nakhleh, L.,
“Confounding Factors in {HGT} Detection: Statistical Error, Coalescent Effects, and Multiple Solutions”,
Journal of Computational Biology, vol. 14, pp. 517-535, 2007.
H. Zafar, Navin, N., Nakhleh, L., and Chen, K.,
“Computational approaches for inferring tumor evolution from single-cell genomic data”,
Current Opinion in Systems Biology, vol. 7, pp. 16-25, 2017.
ZafarEtAl-Rev2017.pdf (1.34 MB)